![]() Core biopsies, which preserve tissue architecture, should not be confused with fine-needle aspiration specimens, which are analyzed using cytopathology techniques. Types of biopsies include core biopsies, which are obtained through the use of large-bore needles, sometimes under the guidance of radiological techniques such as ultrasound, CT scan, or magnetic resonance imaging. ![]() Ī biopsy is a small piece of tissue removed primarily for the purposes of surgical pathology analysis, most often in order to render a definitive diagnosis. ![]() There are two major types of specimens submitted for surgical pathology analysis: biopsies and surgical resections. This is usually performed by a combination of gross (i.e., macroscopic) and histologic (i.e., microscopic) examination of the tissue, and may involve evaluations of molecular properties of the tissue by immunohistochemistry or other laboratory tests. The practice of surgical pathology allows for definitive diagnosis of disease (or lack thereof) in any case where tissue is surgically removed from a patient. Surgical pathology involves gross and microscopic examination of surgical specimens, as well as biopsies submitted by surgeons and non- surgeons such as general internists, medical subspecialists, dermatologists, and interventional radiologists. Surgical pathology is the most significant and time-consuming area of practice for most anatomical pathologists. This is a section of tissue, stained with hematoxylin & eosin, and viewed on a microscope slide
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